Depression

Depression-related research

Select a stress paradigm based on the target and intervention, then organize behavioral and mechanistic validation.

Discuss a model study

Model strategy

Match stress paradigm, intervention window and behavioral endpoints to the study goal.

Match the model and study conditions to candidate mechanism, intervention stage and target tissue.

CUMS

Chronic unpredictable mild stress

CSDS

Chronic social defeat stress

CRS

Chronic restraint stress

Evaluation endpoints

  • 01Sucrose preference
  • 02Forced swim and tail suspension
  • 03Open field and general activity
  • 04Target-matched molecular and tissue assays

Project discussion & study design

Share candidate type, target, intended route and existing results so we can define primary endpoints, groups and study cadence.

View related service

Related research directions

Technical contact

Discuss your target, model or delivery question and learn about study plans, project scope and pricing.